Risk factors for pneumonic and ulceroglandular tularaemia in Finland: a population-based case-control study
| Autor: | Jukka Ollgren, P. Klemets, S. Nikkari, E. Pekkanen, J. P. Nuorti, J. Saikku, H. Syrjala, Markku Kuusi, I. Pietarinen, Heidi Rossow |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Veterinary medicine medicine.medical_specialty Adolescent Epidemiology Population Insect bites and stings Young Adult Risk Factors Skin Ulcer medicine Odds Ratio Animals Humans Young adult education Child Epidemics Lymphatic Diseases Tularemia Disease burden Finland Aged Aged 80 and over education.field_of_study business.industry Diptera Case-control study Infant Insect Bites and Stings Agriculture Bayes Theorem Odds ratio Pneumonia Middle Aged medicine.disease Original Papers Confidence interval 3. Good health Infectious Diseases Culicidae Logistic Models Case-Control Studies Child Preschool Female business Demography |
| Zdroj: | Epidemiol Infect |
| Popis: | SUMMARYFew population-based data are available on factors associated with pneumonic and ulceroglandular type B tularaemia. We conducted a case-control study during a large epidemic in 2000. Laboratory-confirmed case patients were identified through active surveillance and matched control subjects (age, sex, residency) from the national population information system. Data were collected using a self-administered questionnaire. A conditional logistic regression model addressing missing data with Bayesian full-likelihood modelling included 227 case patients and 415 control subjects; reported mosquito bites [adjusted odds ratio (aOR) 9·2, 95% confidence interval (CI) 4·4–22, population-attributable risk (PAR) 82%] and farming activities (aOR 4·3, 95% CI 2·5–7·2, PAR 32%) were independently associated with ulceroglandular tularaemia, whereas exposure to hay dust (aOR 6·6, 95% CI 1·9–25·4, PAR 48%) was associated with pneumonic tularaemia. Although the bulk of tularaemia type B disease burden is attributable to mosquito bites, risk factors for ulceroglandular and pneumonic forms of tularaemia are different, enabling targeting of prevention efforts accordingly. |
| Databáze: | OpenAIRE |
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