Estimation of 24-hour polyamine intake from mature human milk
| Autor: | ER Boersma, Frits A. J. Muskiet, B Dorhout, M Huisman, Aw Kingma, CM vanBeusekom, E deHoog |
|---|---|
| Přispěvatelé: | Lifestyle Medicine (LM) |
| Jazyk: | angličtina |
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
Time Factors LACTATION polyamines growth CLINICAL-APPLICATIONS Mammary gland INTESTINAL MATURATION Spermine Urine Biology Breast milk SPERMIDINE chemistry.chemical_compound Internal medicine Lactation Putrescine medicine INFANT FORMULAS Humans URINE RAT MILK development Milk Human infants Gastroenterology human milk Spermidine medicine.anatomical_structure Endocrinology chemistry Pediatrics Perinatology and Child Health ACID Female Polyamine milk polyamine origin |
| Zdroj: | Journal of Pediatric Gastroenterology and Nutrition, 23(3), 298-302. Lippincott Williams and Wilkins |
| ISSN: | 0277-2116 |
| Popis: | It has been suggested that milk polyamines stimulate GI tract proliferation and maturation in newborns. We determined human milk polyamine concentrations and estimated 24-h outputs on days 16 +/- 4 (n = 98), 44 +/- 3 (n = 97) and 91 +/- 6 (n = 25) after delivery. Median concentrations in micromolars were, respectively, putrescine 0.77, 0.63, and 0.63; spermidine 4.54, 3.07, and 2.73; spermine 3.76, 2.90, and 2.22; and total polyamines 9.82, 6.83, and 5.71. Concentrations of spermidine, spermine, and total polyamines decreased during the observation period. Putrescine, spermidine, and spermine milk/maternal plasma ratios were estimated to be 16-19, 14-24, and 44-75, respectively. It would appear that milk polyamines are derived from the high polyamine contents in the mammary gland and that they may be important in infant nutrition. |
| Databáze: | OpenAIRE |
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