Nasopharyngeal endoscopic resection in the management of selected malignancies: ten-year experience
| Autor: | A. Bolzoni Villaret, D Tomenzoli, S. Mauri, Andrea Bizzoni, Iacopo Dallan, Paolo Battaglia, M. Bignami, Piero Nicolai, Paolo Castelnuovo |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Eustachian tube Kaplan-Meier Estimate Malignancy medicine Parapharyngeal space Humans Endoscopic resection Sinus (anatomy) Aged Nasopharyngeal cancer medicine.diagnostic_test business.industry Cancer Endoscopy Nasopharyngeal Neoplasms General Medicine Middle Aged medicine.disease Surgery medicine.anatomical_structure Otorhinolaryngology Feasibility Studies Female Neoplasm Recurrence Local business |
| Popis: | Objective To evaluate the feasibility of endoscopic surgery in the management of selected nasopharyngeal cancers. Three different types of nasopharyngeal endoscopic resections (NER) are described. Method of study From January 1997 to October 2008, 17 consecutive patients (mean age: 50 years) with previously untreated (5) or recurrent nasopharyngeal tumours (12) were treated with curative intent by pure endoscopic resection. The extent of surgical resection was classified as follows: type I NER: resection limited to the postero-superior nasopharyngeal wall; type 2 NER: resection superiorly extended to the sphenoid sinus; type 3 NER: resection with lateral extension including the cartilaginous portion of the Eustachian tube and parapharyngeal space. Results Type 1 NER was performed in 4 cases, type 2 in 6, and type 3 in 7. No intra- or post-operative complications were observed. Mean hospitalization time was 4 days (range: 1-7). Follow-up ranged from 10 to 138 months (mean: 41.2±38). At the time of writing, 12 (71/%) patients were free of disease, 3 (17%) alive with disease, and 2 (12%) dead of disease. Conclusions NER is a feasible surgical technique that can be tailored in relation to tumour extension. Larger series and longer follow-up are needed to further validate the long-term results. |
| Databáze: | OpenAIRE |
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