Simplification of a Septic Shock Endotyping Strategy for Clinical Application
| Autor: | Christopher Lindsell, Hector Wong, Timothy Sweeney |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Genotype Extramural business.industry Septic shock Genetic Variation 030208 emergency & critical care medicine Critical Care and Intensive Care Medicine medicine.disease Shock Septic 03 medical and health sciences Pediatric patient 0302 clinical medicine 030228 respiratory system Shock (circulatory) Correspondence medicine Humans Biomarker (medicine) Genetic Predisposition to Disease medicine.symptom Intensive care medicine business |
| Zdroj: | American Journal of Respiratory and Critical Care Medicine. 195:263-265 |
| ISSN: | 1535-4970 1073-449X |
| Popis: | Methods and compositions disclosed herein generally relate to methods of identifying, validating, and measuring clinically relevant, quantifiable biomarkers of diagnostic and therapeutic responses for blood, vascular, cardiac, and respiratory tract dysfunction, particularly as those responses relate to septic shock in pediatric patients. In particular, the invention relates to identifying two or more biomarkers associated with septic shock in pediatric patients, obtaining a sample from a pediatric patient having at least one indication of septic shock, then quantifying from the sample an amount of two or more of said biomarkers, wherein the level of said biomarker correlates with a predicted outcome. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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