Dynamic DNA Methylation in Plant Growth and Development
| Autor: | Qiang Han, Matthew Mosley, Jacob K Pearson, Arthur Bartels, Liam Stacey, Hannah Gaynier, Tzung-Fu Hsieh, Pooja Nair, Qi Qing Huang, Yong-Qiang Charles An, Wenyan Xiao |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Transposable element Plant Development plant Review Biology methylome Genome Catalysis Epigenesis Genetic Inorganic Chemistry lcsh:Chemistry 03 medical and health sciences Gene Expression Regulation Plant Gene expression Epigenetics Physical and Theoretical Chemistry Molecular Biology Gene development lcsh:QH301-705.5 Spectroscopy Genetics DNA methylation epigenetics Organic Chemistry Gene Expression Regulation Developmental food and beverages General Medicine Methylation dynamics transposable element Computer Science Applications 030104 developmental biology lcsh:Biology (General) lcsh:QD1-999 gene expression Genomic imprinting seed |
| Zdroj: | International Journal of Molecular Sciences, Vol 19, Iss 7, p 2144 (2018) International Journal of Molecular Sciences |
| ISSN: | 1422-0067 |
| Popis: | DNA methylation is an epigenetic modification required for transposable element (TE) silencing, genome stability, and genomic imprinting. Although DNA methylation has been intensively studied, the dynamic nature of methylation among different species has just begun to be understood. Here we summarize the recent progress in research on the wide variation of DNA methylation in different plants, organs, tissues, and cells; dynamic changes of methylation are also reported during plant growth and development as well as changes in response to environmental stresses. Overall DNA methylation is quite diverse among species, and it occurs in CG, CHG, and CHH (H = A, C, or T) contexts of genes and TEs in angiosperms. Moderately expressed genes are most likely methylated in gene bodies. Methylation levels decrease significantly just upstream of the transcription start site and around transcription termination sites; its levels in the promoter are inversely correlated with the expression of some genes in plants. Methylation can be altered by different environmental stimuli such as pathogens and abiotic stresses. It is likely that methylation existed in the common eukaryotic ancestor before fungi, plants and animals diverged during evolution. In summary, DNA methylation patterns in angiosperms are complex, dynamic, and an integral part of genome diversity after millions of years of evolution. |
| Databáze: | OpenAIRE |
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