Pathogenetic factors of experimental photogenic epilepsy
Autor: | Kryzhanovskiĭ Gn, Konnikov Ba, Rekhtman Mb |
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Rok vydání: | 1979 |
Předmět: |
Male
business.industry Geniculate Bodies Electroencephalography Sensory system General Medicine Epileptogenesis General Biochemistry Genetics and Molecular Biology Photogenic epilepsy Rats Visual cortex medicine.anatomical_structure Seizures Geniculate body Animals Medicine Evoked potential business Local injection Evoked Potentials Neuroscience Pathological Photic Stimulation Visual Cortex |
Zdroj: | Bulletin of Experimental Biology and Medicine. 87:8-12 |
ISSN: | 1573-8221 0007-4888 |
DOI: | 10.1007/bf00802340 |
Popis: | The character of formation of an experimental syndrome of photogenic epilepsy, obtained by creating a generator of pathologically enhanced excitation in the lateral geniculate body by local injection of tetanus toxin, was studied in chronic experiments on rats. The initial manifestations appearing in the animals were shown to be due to pathological enhancement of specific sensory excitation in the lateral geniculate body and to be accompanied by a marked increase in amplitude of the evoked potential in the visual cortex. The subsequent development of a neuropathological syndrome was connected with diffuse disturbances of rhythmic electrical activity of the brain, characteristic of a state of increased epileptic predisposition in the experimental animals. The results of these experiments indicate an important role of specific and nonspecific factors of epileptogenesis in the formation of experimental photogenic epilepsy. |
Databáze: | OpenAIRE |
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