Composite Tissue Allotransplantation: Hand Transplantation and Beyond
| Autor: | Jaimie T. Shores, Gerald Brandacher, Vijay S. Gorantla, Stefan Schneeberger, WP Lee |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Graft Rejection
Immunosuppression Therapy medicine.medical_specialty Reconstructive surgery business.industry medicine.medical_treatment Hand Transplantation Immunosuppression Plastic Surgery Procedures Composite Tissue Allotransplantation Quality of life (healthcare) Transplantation Immunology Tissue Transplantation Humans Transplantation Homologous Medicine Orthopedics and Sports Medicine Surgery business Intensive care medicine Hand transplantation Screening procedures |
| Zdroj: | American Academy of Orthopaedic Surgeon. 18:127-131 |
| ISSN: | 1067-151X |
| DOI: | 10.5435/00124635-201003000-00001 |
| Popis: | Recent advances in transplant immunology are shifting the focus from immunosuppression to immunoregulation, making composite tissue allotransplantation with novel and less potent immunosuppressive regimens a possibility. Hand transplantation has been the most frequently performed human composite tissue allotransplantation, with more than 50 upper extremity-based transplants done worldwide. Further research is needed regarding immunomodulating protocols, and careful oversight and individualized screening procedures will be required as patients seeking improved quality of life through human composite tissue allotransplantation come to accept a certain level of risk in these experimental procedures. Still, composite tissue allotransplantation offers to advance transplant medicine and reconstructive surgery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|