Community-onset healthcare-related urinary tract infections: Comparison with community and hospital-acquired urinary tract infections
| Autor: | Juan Pablo Horcajada, Luisa Sorlí, Hernando Knobel, Santiago Grau, Milagro Montero, Margarita Salvadó, Silvia Aguilar-Duran, Julià Gómez |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Microbiology (medical) medicine.medical_specialty Pediatrics Urinary system Drug resistance urologic and male genital diseases Cohort Studies Age Distribution Diabetes mellitus Drug Resistance Bacterial Epidemiology medicine Humans Prospective Studies Prospective cohort study Survival analysis Aged Aged 80 and over Cross Infection Bacteria business.industry Bacterial Infections Middle Aged medicine.disease Antimicrobial Survival Analysis female genital diseases and pregnancy complications Anti-Bacterial Agents Community-Acquired Infections Treatment Outcome Infectious Diseases Urinary Tract Infections Female business Cohort study |
| Zdroj: | Journal of Infection. 64:478-483 |
| ISSN: | 0163-4453 |
| DOI: | 10.1016/j.jinf.2012.01.010 |
| Popis: | To analyze the characteristics of infection, adequacy of empirical treatment and outcome of patients with community-onset healthcare-associated (HCA) urinary tract infections (UTI) and compare them with hospital (HA) and community-acquired (CA) UTI.Prospective observational cohort study performed at a university 600-bed hospital between July 2009 and February 2010. Patients with UTI requiring hospital admission were included. Epidemiological, clinical and outcome data were recorded.251 patients were included. Patients with community-onset HCA UTI were older, had more co-morbidities and had received previous antimicrobial treatment more frequently than CA UTI (p = 0.02, p = 0.01 and p0.01). ESBL-Escherichia coli and Pseudomonas aeruginosa infections were more frequent in HCA than in CA UTI (p = 0.03 and p0.01). Inadequate empirical treatment was not significantly different between community-onset HCA and CA. Factors related to mortality were P. aeruginosa infection (OR 6.51; 95%CI: 1.01-41.73), diabetes mellitus (OR 22.66; 95%CI: 3.61-142.21), solid neoplasia (OR 22.48; 95%CI: 3.38-149.49) and age (OR 1.15; 95%CI 1.03-1.28).Epidemiological, clinical and microbiological features suggest that community-onset HCA UTI is different from CA and similar to HA UTI. However, in our series inadequate empirical antimicrobial therapy and mortality were not significantly higher in community-onset HCA than in CA UTI. |
| Databáze: | OpenAIRE |
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