Core–Shell Structured Porous Calcium Phosphate Bioceramic Spheres for Enhanced Bone Regeneration

Autor:	Yuangang Wu, Long Yang, Li Chen, Mengyu Geng, Zhengyi Xing, Siyu Chen, Yi Zeng, Jinhan Zhou, Kaibo Sun, Xiao Yang, Bin Shen
Rok vydání:	2022
Předmět:	Calcium Phosphates Bone Regeneration Durapatite Osteogenesis Alginates Animals General Materials Science Hydrogen Peroxide Hydroxyapatites Porosity
Zdroj:	ACS Applied Materials & Interfaces. 14:47491-47506
ISSN:	1944-8252 1944-8244
Popis:	Adequate new bone regeneration in bone defects has always been a challenge as it requires excellent and efficient osteogenesis. Calcium phosphate (CaP) bioceramics, including hydroxyapatite (HA) and biphasic calcium phosphates (BCPs), have been extensively used in clinical bone defect filling due to their good osteoinductivity and biodegradability. Here, for the first time, we designed and fabricated two porous CaP bioceramic granules with core-shell structures, named in accordance with their composition as BCP@HA and HA@BCP (core@shell). The spherical shape and the porous structure of these granules were achieved by the calcium alginate gel molding technology combined with a H
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b10873467a7e2a5c4946228030c36f https://doi.org/10.1021/acsami.2c15614 Zobrazit plný text záznamu