Synthesis of Highly Functionalized 1,3-Oxathiazoles via an Unusual [4+1] Annulation alpha,alpha'-Dioxothione with 1,2-Diaza-1,3-dienes

Autor:	Stefano Menichetti, Caterina Viglianisi, Orazio A. Attanasi, Gianfranco Favi, Fabio Mantellini, Giada Moscatelli
Jazyk:	angličtina
Rok vydání:	2012
Předmět:	Phthalimide chemistry.chemical_compound Annulation chemistry Present method Yield (chemistry) Organic Chemistry Michael reaction Pyrazolone medicine Medicinal chemistry medicine.drug
Popis:	The present method provides highly functionalized 1,3-oxathioles through an unusual base-promoted [4+1] annulation between α,α'-dioxothione, generated in situ from a phthalimide precursor, and 1,2-diaza-1,3-dienes. An intriguing scaffold comprised of spiro-fused oxathiole and pyrazolone components was also obtained in moderate yield.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a9562d26cb5398f801c6824059ce52 https://hdl.handle.net/11576/2579977 Zobrazit plný text záznamu