Incidence and risk factors of posttraumatic seizures following traumatic brain injury: A Traumatic Brain Injury Model Systems Study
Autor: | Jerzy P. Szaflarski, Joseph A. Rosenthal, Mary Jo Pugh, Tamara Bushnik, Jason W. Krellman, Amy K. Wagner, Laura E. Dreer, Anthony Fabio, William C. Walker, Flora M. Hammond, Allen W. Brown, Douglas Johnson-Greene, Anne C. Ritter, Timothy Shea, Ross Zafonte |
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Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Subarachnoid hemorrhage Adolescent Traumatic brain injury Poison control macromolecular substances Statistics Nonparametric Cohort Studies 03 medical and health sciences Young Adult 0302 clinical medicine Risk Factors Internal medicine Brain Injuries Traumatic medicine Humans Cumulative incidence business.industry Incidence (epidemiology) Incidence Age Factors medicine.disease Epilepsy Post-Traumatic Surgery 030104 developmental biology Neurology Relative risk Cohort Female Neurology (clinical) business 030217 neurology & neurosurgery Cohort study |
Zdroj: | Epilepsia. 57(12) |
ISSN: | 1528-1167 |
Popis: | SummaryObjective Determine incidence of posttraumatic seizure (PTS) following traumatic brain injury (TBI) among individuals with moderate-to-severe TBI requiring rehabilitation and surviving at least 5 years. Methods Using the prospective TBI Model Systems National Database, we calculated PTS incidence during acute hospitalization, and at years 1, 2, and 5 postinjury in a continuously followed cohort enrolled from 1989 to 2000 (n = 795). Incidence rates were stratified by risk factors, and adjusted relative risk (RR) was calculated. Late PTS associations with immediate ( 7 day) versus no seizure prior to discharge from acute hospitalization was also examined. Results PTS incidence during acute hospitalization was highest immediately ( |
Databáze: | OpenAIRE |
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