Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients

Autor: Victor Revin, Larisa Balykova, Sergey Pinyaev, Ilya Syusin, Olga Radaeva, Nadezhda Revina, Yuliya Kostina, Evgeniy Kozlov, Vera Inchina, Igor Nikitin, Alexandr Salikov, Ilya Fedorov
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Biomedicines; Volume 10; Issue 3; Pages: 553
ISSN: 2227-9059
DOI: 10.3390/biomedicines10030553
Popis: In this paper, the erythrocytes of healthy donors and people with a confirmed diagnosis of COVID-19 were tested by Raman spectroscopy and laser interference microscopy. We argue that erythrocytes (red blood cells) in COVID-19 patients have an irregular shape, and their morphometric characteristics are impaired in comparison to healthy red blood cells. Raman spectroscopy also allows us to detect a decreased oxygen transport function of these erythrocytes. The combination of these methods—Raman spectroscopy and laser interference microscopy—is a highly effective method for the diagnosis of SARS-CoV-2.
Databáze: OpenAIRE