A Quantitative Test of Long-range Correlations and Compositional Fluctuations in DNA Sequences
| Autor: | C. Aris Chatzidimitriou-Dreismann, R. M. Friedrich Streffer, Dan Larhammar |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Genetics
Stochastic Processes Quantitative Biology::Biomolecules Sequence Base Sequence DNA Saccharomyces cerevisiae Composition (combinatorics) Biology Quantitative Biology::Genomics Biochemistry Genome Introns DNA sequencing Mice Fractals Fractal Sequence Homology Nucleic Acid Exponent Animals Humans A-DNA Chromosomes Fungal Biological system Scaling |
| Zdroj: | European Journal of Biochemistry. 224:365-371 |
| ISSN: | 1432-1033 0014-2956 |
| DOI: | 10.1111/j.1432-1033.1994.00365.x |
| Popis: | Recent findings concerning long-range correlations and fractals in intron-containing DNA sequences of living organisms are tested qualitatively and quantitatively. Extending previous studies, we demonstrate that these findings are trivially equivalent to variations of the base-pair composition in different regions of a DNA sequence. It is shown explicitly that a well-defined scaling or fractal exponent does not exist anywhere. Comparisons of natural DNAs with computer-generated, artificial sequences are made. The present study reveals that certain natural DNA sequences (especially those with compact genomes) do have stochastic characteristics which are intrinsically different from artificial sequences. The results for 21 DNA sequences of various types from widely different taxa are reported. |
| Databáze: | OpenAIRE |
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