Outcome of Dialysis-Requiring Acute Kidney Injury in Patients With Infective Endocarditis: A Nationwide Study
| Autor: | Jawad H. Butt, Eva Havers-Borgersen, Lauge Østergaard, Emil L. Fosbøl, Lars Køber, Christian Torp-Pedersen, Anne Lise Kamper, Niels Eske Bruun, Jeppe Kofoed Petersen, Andreas Dalsgaard Jensen, Mavish S. Chaudry |
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| Rok vydání: | 2020 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty medicine.medical_treatment Aftercare 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Endocarditis/complications Renal Dialysis Risk Factors Internal medicine Cardiac valve medicine Humans In patient Hospital Mortality 030212 general & internal medicine Dialysis Endocarditis business.industry Acute kidney injury Acute Kidney Injury After discharge medicine.disease Patient Discharge Confidence interval Infectious Diseases Infective endocarditis Hemodialysis business Acute Kidney Injury/epidemiology |
| Zdroj: | Petersen, J K, Jensen, A D, Bruun, N E, Kamper, A L, Butt, J H, Havers-Borgersen, E, Chaudry, M S, Torp-Pedersen, C, Køber, L, Fosbøl, E L & Østergaard, L 2021, ' Outcome of Dialysis-Requiring Acute Kidney Injury in Patients With Infective Endocarditis : A Nationwide Study ', Clinical Infectious Diseases, vol. 72, no. 9, pp. e232-e239 . https://doi.org/10.1093/cid/ciaa1017 |
| ISSN: | 1537-6591 1058-4838 |
| Popis: | Background Infective endocarditis (IE) may be complicated by acute kidney injury, yet data on the use of dialysis and subsequent reversibility are sparse. Methods Using Danish nationwide registries, we identified patients with first-time IE from 2000 to 2017. Dialysis-naïve patients were grouped into: those with and those without dialysis during admission with IE. Continuation of dialysis was followed 1 year postdischarge. Multivariable adjusted Cox proportional hazard analysis was used to examine 1-year mortality for patients surviving IE according to use of dialysis. Results We included 7307 patients with IE; 416 patients (5.7%) initiated dialysis treatment during admission with IE and these were younger, had more comorbidities and more often underwent cardiac valve surgery compared with nondialysis patients (47.4% vs 20.9%). In patients with both cardiac valve surgery and dialysis treatment (n = 197), 153 (77.7%) initiated dialysis on or after the date of surgery. The in-hospital mortality was 40.4% and 19.0% for patients with and without dialysis, respectively (P Conclusion In dialysis-naïve patients with IE, approximately 1 in 20 patients initiated dialysis treatment during admission with IE. Dialysis identified a high-risk group with an in-hospital mortality of 40% and an approximate 20% risk of continued dialysis. Those with dialysis during admission with IE showed worse long-term outcomes than those without. |
| Databáze: | OpenAIRE |
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