Mechanism of the Rearrangement of Quinamine to IsoQuinamine

Autor: Robert Robinson, L. J. Goldsworthy, C. C. J. Culvenor, K. S. Kirby
Rok vydání: 1950
Předmět:
Zdroj: Nature. 166:105-106
ISSN: 1476-4687
0028-0836
DOI: 10.1038/166105a0
Popis: THE transformation of quinamine to isoquinamine is brought about by the action of hot isoamyl alcoholic sodium isoamyloxide on quinamine1. (We have found that, under milder conditions with ethanolic sodium ethoxide, the alkaloid is first epimerized with partial formation of epiquinamine, almost certainly identical with conquinamine.)
Databáze: OpenAIRE