Autor:	Sophie Mockly, Hervé Seitz
Rok vydání:	2022
Předmět:	Cancer Research Oncology
Zdroj:	British journal of cancer.
ISSN:	1532-1827
Popis:	A prolific scientific literature attributes pro- or anti-oncogenic properties to many human microRNAs ("miRNAs"). While many of these studies are based on unpersuasive analyses, one candidate suppressor tumour miRNA, miR-34a, appeared convincing enough to be administered to human patients in a clinical trial-with disappointing outcomes. Here, we review possible reasons for that failure, and their implications for other miRNAs.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f08a9a2bf8bbac656b337d91412a1534 https://pubmed.ncbi.nlm.nih.gov/36550206 Zobrazit plný text záznamu Full text from SpringerLink