Atrophic Dermatofibroma: A Unique Dermatofibroma Variant
| Autor: | Antoanella Calame, Philip R. Cohen, Nikolas Gutierrez, Christof Erickson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Acanthosis Dermatology 030204 cardiovascular system & hematology fibers Dermatofibroma fibroblast Lesion 03 medical and health sciences 0302 clinical medicine Atrophy atrophy elastic Biopsy medicine medicine.diagnostic_test business.industry atrophic dermatofibroma General Engineering Hyperplasia medicine.disease Hyperpigmentation hyperpigmentation medicine.symptom business Atrophic dermatofibroma 030217 neurology & neurosurgery Family/General Practice acanthosis |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Dermatofibromas are benign skin tumors with several variants, including the rare, uncommonly described atrophic dermatofibroma. To the best of our knowledge, there are currently 105 reported cases of atrophic dermatofibromas in the literature. This variant typically presents as a flat or depressed macule whose color can range from brown to white to red; in contrast to classic dermatofibromas that typically occur on the legs, atrophic dermatofibromas have a tendency to occur on the upper back and arms. An atrophic dermatofibroma can be clinically diagnosed; however, given the broad spectrum of clinical features of this lesion, a biopsy may be required. Characteristic pathologic features include epidermal acanthosis, basilar hyperpigmentation, fibroblast hyperplasia, and decreased or absent elastic fibers within the lesion. The pathogenesis of this lesion is not yet fully understood; however, it has been postulated that the loss of elastic fibers plays a key role in its development and characteristic atrophic appearance. We present the cases of two men with biopsy-confirmed atrophic dermatofibromas: a 47-year-old man with a pigmented macule on the right upper back and a 68-year-old man with an erythematous patch on the left posterolateral shoulder. The clinical and pathologic features of atrophic dermatofibromas are also summarized. |
| Databáze: | OpenAIRE |
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