A low-noise preamplifier for multisite recording of brain multi-unit activity in freely moving animals
| Autor: | T.J. Marczynski, Imre Szabó |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Physics
Preamplifier business.industry General Neuroscience Acoustics Instrumentation Action Potentials Brain Neurophysiology Low-noise amplifier Electrodes Implanted Rats Stereotaxic Techniques Electrophysiology Common-mode rejection ratio Interference (communication) Electrode Animals Instrumentation amplifier Telecommunications business Microelectrodes Monitoring Physiologic |
| Zdroj: | Journal of neuroscience methods. 47(1-2) |
| ISSN: | 0165-0270 |
| Popis: | A novel FET instrumentation amplifier is described which, as compared to most traditional operational FET preamplifiers, is characterized by an about 7–10 times lower intrinsic electronic noise and a higher common mode rejection. This allows discrimination of single units from multi-unit recording, even if the action potential amplitudes are as small as 20–30 μV and the units are located more than 100 μm away from the electrode tips. Such a distant and chronic recording may be expected to reduce the possibility of mechanical interference with functions of neuronal membrane and its immediate environment, and may be suitable for studying changes in functional connectivities among neurons during the animal's behavior and learning. |
| Databáze: | OpenAIRE |
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