Kidney transplantation in systemic lupus erythematosus: Outcomes and prognosis
| Autor: | Laura E. Díaz-González, Roberto Marcén-Letosa, Fernando Liaño García, Saúl Pampa-Saico, Ana Fernández-Rodríguez, Sara Jiménez-Álvaro |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Lupus nephritis Disease Gastroenterology 03 medical and health sciences 0302 clinical medicine Glomerulonephritis immune system diseases Internal medicine Medicine Humans 030212 general & internal medicine skin and connective tissue diseases Kidney transplantation Retrospective Studies Kidney business.industry Graft Survival Middle Aged medicine.disease Prognosis Kidney Transplantation Lupus Nephritis Survival Rate medicine.anatomical_structure Treatment Outcome Graft survival Female business |
| Zdroj: | Medicina clinica. 153(12) |
| ISSN: | 1578-8989 |
| Popis: | Introduction The outcome and prognosis of systemic lupus erythematosus (SLE) in long-term kidney transplantation (KT) is variable. The objective of this study was to analyze the survival of the graft and the patient, comparing rates with a control group (primary glomerulonephritis [PGN]). Materials and methods Forty-three patients receiving a KT with diagnosis of lupus nephritis (LN) and 367 patients with PGN were compared between January 1980 and December 2014. The survival causes of loss and death of the graft and the patient were analyzed. Results There were no significant differences between the variables analyzed. The graft survival at five years (80% SLE vs. 70% PGN) and 10 years (63% SLE vs. 55% PGN) and the patient at 5 years (90% SLE vs. 90% PGN) and 10 years (76% LES vs. 79% PGN) were similar. Not recurrence of LN was observed in any patient. Conclusions Patients with SLE are similar candidates to KT than that with other immunological kidney diseases. There was no recurrence of the disease in any patient. |
| Databáze: | OpenAIRE |
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