α-Carbonyl radicals for total synthesis of natural products

Autor:	Wei‐Hong Tseng, Shih-Jung Huang, Ruey‐Torn Chiou, Shin-Hong Lih, Nei‐Tung Yau, Chin-Kang Sha, Jenn‐Fenn Young, Tsong‐Shin Jean
Rok vydání:	1996
Předmět:	chemistry.chemical_compound chemistry Bicyclic molecule General Chemical Engineering Radical Intramolecular cyclization Side chain Organic chemistry Total synthesis General Chemistry Vinylsilane Medicinal chemistry
Zdroj:	Pure and Applied Chemistry. 68:687-689
ISSN:	1365-3075 0033-4545
DOI:	10.1351/pac199668030687
Popis:	Intramolecular cyclization of α-carbonyl radicals to the trimethylsilylacetylenic side chain gives bicyclic vinylsilane ketones and enones. Application of this cyclization to total synthesis of (±)-modhephene is described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f083124dd1fd85732032fbad8cbd1dd6 https://doi.org/10.1351/pac199668030687 Zobrazit plný text záznamu