Long-range studies of the biologic behavior of the human uterine cervix
| Autor: | David V. Brown, Russell R. de Alvarez, Warren R. Fullington, David C. Figge |
|---|---|
| Rok vydání: | 1958 |
| Předmět: |
Gynecology
Pathology Pregnancy medicine.medical_specialty education.field_of_study Range (biology) business.industry Population Obstetrics and Gynecology Cervical Metaplasia medicine.disease Squamous metaplasia Menopause Uterine cervix medicine.anatomical_structure Metaplasia medicine Cervix neoplasm Epithelial hyperplasia medicine.symptom education business Cervix Leukorrhea |
| Zdroj: | American Journal of Obstetrics and Gynecology. 75:945-956 |
| ISSN: | 0002-9378 |
| DOI: | 10.1016/0002-9378(58)90809-3 |
| Popis: | In an attempt to define the etiological factors important in the genesis of carcinoma of the uterine cervix, a large group of normal women has been followed for over 5 years. An initial careful history and physical examination have been followed by periodic pelvic examinations, vaginal cytology, and biopsies of the cervix. There appears to be a definite relationship between cervical metaplasia and age, as well as a correlation between metaplasia and the presence of cervical eversion in the patient under the age of 40 years. The suggested relationships of pregnancy, the menopause, and other uterine disease were found to represent merely the altered prevalence found within the age groups involved. In this series no relationship could be shown between cervical metaplasia and race, marital status, menarche, time of menopause, type of menopause (physiologic or surgical), pregnancy, leukorrhea, bloody discharge, history of venereal disease, use of contraceptives, circumcision of husband, height, weight, body type, size of breasts, presence of enlarged inguinal nodes, gravidity, parity, clinical parity of the cervix, type of cervical mucosa, size or irregularity of the uterus, adnexal or rectal pathology. Because of the low incidence of cervical malignancy in the general population and the comparatively small group of such patients studied, no direct evidence has yet been obtained concerning the relationship between cervical metaplasia and cervical malignancy. Continuation of this study with the accumulation of additional data may provide definitive information and answers to these problems. |
| Databáze: | OpenAIRE |
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