Relationship of chronic endometritis with chronic deciduitis in cases of miscarriage

Autor:	Akiko Nakamura, Ryoji Kushima, Fuminori Kimura, Akiko Takashima, Jun Kitazawa, Akie Takebayashi, Takashi Murakami, Aina Morimune, Akimasa Takahashi, Takuro Kubo, Shoji Kaku
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Adult Male Abortion Habitual medicine.medical_specialty Pregnancy Rate Plasma cell Miscarriage Sensitivity and Specificity Gastroenterology lcsh:Gynecology and obstetrics Endometrium Young Adult 03 medical and health sciences 0302 clinical medicine Pregnancy Internal medicine Decidua Prevalence medicine Humans In patient lcsh:RG1-991 030304 developmental biology Chronic deciduitis 0303 health sciences 030219 obstetrics & reproductive medicine business.industry Incidence lcsh:Public aspects of medicine Pregnancy Outcome First pregnancy Obstetrics and Gynecology lcsh:RA1-1270 General Medicine medicine.disease Pregnancy Complications medicine.anatomical_structure Reproductive Medicine Chronic Disease Chronic endometritis Female Endometritis business Chronic Endometritis Research Article
Zdroj:	BMC Women's Health, Vol 20, Iss 1, Pp 1-6 (2020) BMC Women's Health
ISSN:	1472-6874
DOI:	10.1186/s12905-020-00982-y
Popis:	Background: The presence of chronic deciduitis (CD) was determined in patients diagnosed with or without chronic endometritis (CE) before pregnancy. Objective: To study the effect of CE on decidua in cases of miscarriage. Methods:Decidual tissue was obtained from the patients who miscarried at the first pregnancy within a year after the diagnosis of the presence or absence of CE. The number and distribution pattern of plasma cells stained with CD138 in decidual tissue in 10 high-power fields (HPFs) was examined. The prevalence of CD diagnosed with four different grade; grade 0, no plasma cell in 10 HPFs, thus Non-CD;grade 1, rare single plasma cells; grade 2, rare clusters or more than 5 single cells total; and grade 3, many plasma cells with more than 5 clusters, were examined and compared between Non-CE and CE. Results:The incidence rate of CD of grade2 + 3 was significantly higher in CE than Non-CE (53.8%; 7/13 vs. 0%; 0/13, P < 0.01). Presence of clusters or a number of plasma cells in 10 HPFs of decidua showed a sensitivity of 53.8%, a specificity of 100%, a positive predictive value of 100%, and a negative predictive value of 68.4% for the diagnosis of CE. Conclusion:Presence of clusters of plasma cells or five or more of plasma cells in decidua was found in more than half of CE, but not found in Non-CE. When CD with cluster or five or more of plasma cells is confirmed histologically in miscarriage decidual tissue, the presence of CE before the pregnancy should be suspected.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07c6d24441952f88717ea6823e097e5 http://link.springer.com/article/10.1186/s12905-020-00982-y Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.