Biological monitoring of urinary lead: Preshift and postshift sampling detects efficiently recent lead exposure and signals the need to review and possibly improve controls at work
| Autor: | Bas de Barbanson |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Urinary system Air Pollutants Occupational Toxicology Occupational medicine 03 medical and health sciences 0302 clinical medicine Occupational Exposure Environmental health Humans Medicine Sampling (medicine) Respiratory Protective Devices Workplace Lead (electronics) Personal Protective Equipment Lead tests Netherlands business.industry Construction Industry General Medicine 030104 developmental biology Lead Lead exposure business 030217 neurology & neurosurgery Biological Monitoring |
| Zdroj: | Toxicology Letters. 331:53-56 |
| ISSN: | 0378-4274 |
| DOI: | 10.1016/j.toxlet.2020.05.037 |
| Popis: | The objective of this study is to highlight the effectiveness of urinary lead as an index of recent lead exposure. In the past scientific literature urinary lead has been studied as a parameter for recent lead exposure. It is a reliable indicator for occupational lead exposure. But, strangely enough, nowadays is scarcely used in the Netherlands and worldwide. We performed six field biological monitoring studies of preshift and postshift urinary lead tests during tank maintenance and bridge repair work. Highest values occurred during bridge repair. Mean urinary values were postshift 1,6-5 times higher than preshift values, indicating clearly recent lead exposure and failing protective measures. This is so far we know the first study combining preshift and postshift sampling of urinary lead. We compared our studies with crossectional and follow-up studies in occupational medicine. Our conclusion is that preshift and postshift urinary lead testing is a worker friendly test, ideally for detecting recent lead exposures in the field. It signals the need to review or possibly improve controls at work. There are no safe lead levels, so we recommend to use a target value for urinary lead of3 μg/g creatinine for all lead workers in the Netherlands. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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