The prioritation and gap of preoperative COVID-19 vaccination in cancer surgery of the breast, head and neck, and skin: A cohort study of 367 patients in an Indonesian hospital
| Autor: | Suwardjo Suwardjo, Sumadi Lukman Anwar, Herjuna Hardiyanto, Darwito Darwito, Wirsma Arif Harahap, Roby Cahyono |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
COVID-19 vaccination Coronavirus disease 2019 (COVID-19) business.industry Pulmonary Complication Postoperative complication Cancer Cancer patients General Medicine medicine.disease Vaccination Breast cancer Internal medicine medicine Surgery business Cancer surgery Cohort Study Cohort study |
| Zdroj: | Annals of Medicine and Surgery |
| ISSN: | 2049-0801 |
| DOI: | 10.1016/j.amsu.2021.103089 |
| Popis: | Background Postoperative infection of Coronavirus Disease 2019 (COVID-19) has been associated with higher risks of mortality and pulmonary complication. Preoperative vaccination could significantly prevent postoperative-related mortality and morbidity particularly for cancer patients. Methods Cancer patients who were scheduled for elective major surgery were questioned for status and their willingness to receive COVID-19 vaccination and were prospectively monitored for the presence of postoperative COVID-19 infection and major complications. Results During the period of April–July 2021, 367 patients with median age of 49 years were scheduled for cancer surgery. Procedures for breast cancer were the most frequently performed (N = 166, 45.2%). Surgery procedures with potential aerosol generating procedures (AGPs) were performed in total of 104 patients (28.3%). Only 6 of 367 patients (1.6%) were fully vaccinated in the day of surgery and 351 patients (95.6%) were willing to receive COVID-19 vaccination. Fully vaccinated patients were significantly higher among those who were living in urban areas (OR = 22.897, 95%CI:4.022–130.357, P = 0.0001). Willingness to get the COVID-19 vaccination was significantly higher among female patients (OR = 4.661, 95%CI:1.685–12.896, P = 0.003). Postoperative COVID-19 infection was confirmed in 17 patients (4.6%) and major surgical complications were observed in 12 patients (3.3%). None of preoperatively vaccinated patients experienced postoperative COVID-19 infection or the related major complications. Conclusion Although prioritizing COVID-19 vaccination in preoperative cancer patients has been recommended to prevent postoperative fatalities, only a small proportion of our patients have been vaccinated. Preoperatively vaccinated patients show advantages in the prevention of postoperative COVID-19 infection and major surgery complications. The slow rollout and disparity in the vaccination progress for patients requiring a major cancer surgery need to be specifically addressed. Highlights • Only small proportion of preoperative cancer patients have been fully vaccinated against COVID-19. • There is rural-urban disparity in the preoperative COVID-19 vaccination of cancer patients. • Certain comorbidities are associated with vaccine acceptance among cancer patients. • Preoperative COVID-19 vaccination is potentially beneficial to prevent infection and complication. |
| Databáze: | OpenAIRE |
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