Tip-Enhanced Raman Imaging: An Emergent Tool for Probing Biology at the Nanoscale
| Autor: | Jordan M. Klingsporn, Mark C. Hersam, Nan Jiang, Matthew D. Sonntag, Eric A. Pozzi, Richard P. Van Duyne |
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| Rok vydání: | 2013 |
| Předmět: |
Diffraction
Materials science Analytical technique General Engineering Raman imaging General Physics and Astronomy Nanotechnology Spectrum Analysis Raman Molecular Imaging symbols.namesake Nano symbols Humans General Materials Science Spectroscopy Raman spectroscopy Biology Image resolution Nanoscopic scale |
| Zdroj: | ACS Nano. 7:885-888 |
| ISSN: | 1936-086X 1936-0851 |
| DOI: | 10.1021/nn400560t |
| Popis: | Typically limited by the diffraction of light, most optical spectroscopy methods cannot provide the spatial resolution necessary to characterize specimens at the nanoscale. An emerging exception to this rule is tip-enhanced Raman spectroscopy (TERS), which overcomes the diffraction limit through electromagnetic field localization at the end of a sharp metallic tip. As demonstrated by the Zenobi group in this issue of ACS Nano, TER imaging is an analytical technique capable of providing high-resolution chemical maps of biological samples. In this Perspective, we highlight recent advances and future applications of TER imaging as a technique for interrogating biology at the nanoscale. |
| Databáze: | OpenAIRE |
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