Thiamine tetraphydrofurfuryl disulfide in nutritional polyneuropathy
| Autor: | S. L. H. Notermans, W. Djoenaidi |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Vitamin
Adult Male medicine.medical_specialty Adolescent medicine.medical_treatment Neural Conduction Beriberi Gastroenterology Drug Administration Schedule chemistry.chemical_compound Polyneuropathies Internal medicine medicine Humans Pharmacology (medical) Fursultiamin Infusions Intravenous Developing Countries Biological Psychiatry Thiamine deficiency Aged Neurologic Examination Chemotherapy Clinical Trials as Topic business.industry General Neuroscience Disulfide bond Thiamine Deficiency General Medicine Middle Aged medicine.disease Surgery Sensory function Psychiatry and Mental health Neuropsychology and Physiological Psychology Pyrimidines chemistry Indonesia Thiamine Female business Polyneuropathy Follow-Up Studies |
| Zdroj: | European archives of psychiatry and neurological sciences. 239(4) |
| ISSN: | 0175-758X |
| Popis: | An open trial with thiamine tetrahydrofurfuryl disulphide (TTFD) was carried out on 44 patients with nutritional polyneuropathy who were admitted to the Neurological Department, Dr. Soetomo Hospital, Surabaya, Indonesia, Thirty-four patients showed improvement of their motor functions (P less than 0.01) with slight restoration of sensory function and reflexes (P less than 0.1). Of the 18 patients who were re-examined electrophysiologically 3 months later, 6 showed remarkable improvements. No side-effects were observed during TTFD treatment. It seemed that nutritional polyneuropathy in our low socio-economic patients was mostly caused by thiamine deficiency. |
| Databáze: | OpenAIRE |
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