Cardiorespiratory adaptation to low‐dose dexamethasone for lung disease in extremely preterm infants: A prospective echocardiographic study

Autor: Arvind Sehgal, Marcel F. Nold, Calum T. Roberts, Samuel Menahem
Rok vydání: 2022
Předmět:
Zdroj: The Journal of Physiology. 600:4361-4373
ISSN: 1469-7793
0022-3751
DOI: 10.1113/jp282973
Popis: The cardiovascular impact of dexamethasone (Dex) is not well understood. Most data are obtained from a 6 week, high-dose regimen, and are limited to findings of hypertension and cardiac hypertrophy. The present study ascertained the impact of low-dose Dex on cardiac indices when administered to extremely preterm infants for lung disease. A pre-post intervention prospective echocardiographic (Echo) study was undertaken, with cardiac assessments performed before and within 24 h after completion of first course of therapy (10 day regimen, cumulative 0.89 mg kg
Databáze: OpenAIRE