Silica dust, diesel exhaust, and painting work are the significant occupational risk factors for lung cancer in nonsmoking Chinese men
| Autor: | Hong Qiu, X-r Wang, Lap Ah Tse, IT-s Yu, J S K Au |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male China Cancer Research Pathology medicine.medical_specialty Lung Neoplasms Epidemiology Adenocarcinoma of Lung Adenocarcinoma Tobacco smoke Risk Factors Occupational Exposure Environmental health Paint occupation Odds Ratio medicine Genetic predisposition Humans Risk factor Lung cancer Aged Vehicle Emissions industry business.industry Incidence Incidence (epidemiology) Case-control study Dust Odds ratio respiratory system Middle Aged Prognosis Silicon Dioxide medicine.disease respiratory tract diseases carcinogen Occupational Diseases Oncology Case-Control Studies lung carcinoma business nonsmokers |
| Zdroj: | British Journal of Cancer |
| ISSN: | 1532-1827 0007-0920 |
| DOI: | 10.1038/sj.bjc.6606006 |
| Popis: | Tobacco smoking is the most important risk factor for lung cancer (IARC, 2004), contributing around 80% of lung cancer cases of European men and 58% of Chinese men (Tse et al, 2009a). Other risk factors include occupational exposures to suspected carcinogens, environmental tobacco smoke (ETS), residential radon exposure, and genetic susceptibility (Alberg et al, 2005). Numerous studies have examined the associations between occupational exposures and lung cancer risk, but only a few have explored these in lifelong nonsmoking men (Pohlabeln et al, 2000; Zeka et al, 2006). Smoking is such a strong risk factor of lung cancer (IARC, 2004) that its presence makes it difficulty to examine the effects of occupational exposures with weak to moderate carcinogenicity. Moreover, cigarette smoking may modify the effects of occupational exposures on lung cancer risk (Liddell, 2001; Yu and Tse, 2006). As inadequate consideration of smoking can lead to inaccurate risk estimations, restriction of study subjects to lifelong nonsmokers offers the best way to examine the independent effects of occupational carcinogens. However, in most studies, lung cancers in lifelong nonsmokers are very few ( |
| Databáze: | OpenAIRE |
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