Effect of estrogen on serum DHEA in younger and older women and the relationship of DHEA to adiposity and gender
| Autor: | V. Daniel Castracane, Linda B. Synovitz, Robert R. Kraemer, Lisa G. Johnson, G. R. Kraemer, Terry Gimpel |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
Male medicine.medical_specialty Aging Adolescent medicine.drug_class Endocrinology Diabetes and Metabolism medicine.medical_treatment Dehydroepiandrosterone Body Mass Index Contraceptives Oral Hormonal Endocrinology Internal medicine Medicine Humans Sex Characteristics business.industry Case-control study Hormone replacement therapy (menopause) Estrogens Androgen Adipose Tissue Estrogen Case-Control Studies Female business Body mass index hormones hormone substitutes and hormone antagonists Biomedical sciences Sex characteristics |
| Zdroj: | Metabolism: clinical and experimental. 50(4) |
| ISSN: | 0026-0495 |
| Popis: | This case-controlled study consisted of 2 parts. The objective of part 1 was to determine the relationship between DHEA, body mass index (BMI), and age in young males, young females, and postmenopausal (PM) females. Part 2 examined the effects of estrogen on DHEA by analyzing the relationship between DHEA and age in young females on and off oral contraceptives (OCs) and PM females on and off estrogen or hormone replacement therapy (ERT/HRT). The study was performed at the Obstetrics and Gynecology Clinic, Texas Tech Health Sciences Center-Amarillo, Exercise Physiology Laboratory at Southeastern Louisiana University, and Woman's Health Research Institute, Woman's Hospital, Baton Rouge, LA. Part 1 groups consisted of: (1) young males between the ages of 18 to 40 years; (2) normally cycling females off OCs, ages 18 to 40 years; and (3) PM females older than 40 years not receiving ERT/HRT. Part 2 groups consisted of: (1) normally cycling females on OCs, ages 18 to 40 years;, (2) normally cycling females off OCs, ages 18 to 40 years; (3) PM females 50 years or older not receiving ERT/HRT; and (4) PM females 50 years or older receiving ERT/HRT. The main outcome measure was serum DHEA concentrations. For part 1, there were significant (P |
| Databáze: | OpenAIRE |
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