Asymmetric dearomatization of 2-nitrobenzofurans by organocatalyzed one-step Michael addition to access 3,3'-disubstituted oxindoles

Autor:	Ke-Xin Xie, Yong You, Zhen-Hua Wang, Ming-Qiang Zhou, Jian-Qiang Zhao, Lei Yang, Zhen-Zhen Ge, Wei-Cheng Yuan
Rok vydání:	2020
Předmět:	Chemistry Materials Chemistry Metals and Alloys Ceramics and Composites Michael reaction Enantioselective synthesis One-Step General Chemistry Combinatorial chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials
Zdroj:	Chemical communications (Cambridge, England). 56(17)
ISSN:	1364-548X
Popis:	An efficient enantioselective dearomatization of 2-nitrobenzofurans was realized via an organocatalyzed one-step Michael addition process. This method provides a facile strategy to access a range of structurally diverse 3,3'-disubstituted oxindoles, which feature an intriguing combination of two privileged motifs including 3-pyrrolyl-substituted-oxindoles and 2,3-dihydrobenzofurans substructures, in excellent results.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0630b8130b8a96d96b5449a5bdc24b4 https://pubmed.ncbi.nlm.nih.gov/32016206 Zobrazit plný text záznamu