(–)-Agelasidine A from Agelas clathrodes
| Autor: | José Carlos Roseiro, Maria A. Medeiros, Maria Regina Tavares, Ana Lourenço, Sónia Savluchinske Feio, Maria João Marcelo Curto |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Antifungal
Staphylococcus aureus Magnetic Resonance Spectroscopy medicine.drug_class Staphylococcus Molecular Conformation Agelasidine D Agelas clathrodes Microbial Sensitivity Tests medicine.disease_cause Guanidines General Biochemistry Genetics and Molecular Biology Microbiology medicine Animals Sulfones Bacteriostatic agent Molecular Structure biology biology.organism_classification Anti-Bacterial Agents Sponge Biochemistry Agelas Bacteria medicine.drug |
| Zdroj: | Zeitschrift für Naturforschung C. 61:472-476 |
| ISSN: | 1865-7125 0939-5075 |
| DOI: | 10.1515/znc-2006-7-802 |
| Popis: | (-)-Agelasidine A was identified from the methanol extract of the marine sponge Agelas clathrodes for the first time together with zooanemonin, 1-carboxymethylnicotinic acid, hymenidin, mukanadins A and C, monobromodispacamide, agelasidine D, 2-amide-4-bromopyrrole, O-methyltryptophan and an agelasines mixture. The structures were characterized by spectroscopic methods. (-)-Agelasidine A was tested for antibacterial and antifungal activities and shown to act as a bacteriostatic agent as it inhibited the growth of Staphylococcus aureus and partially the growth of other bacteria. |
| Databáze: | OpenAIRE |
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