Poorly Differentiated Neuroendocrine Carcinoma in a Perigastric Lymph Node from an Unknown Primary Site
| Autor: | Hee Seung Lee, Seung Taik Kim, Ho Chang Lee, Hye Suk Han, Hyun Jung Jeon, Hyo Young Yun, Sung Nam Lim, Ki Hyeong Lee, Ok Jun Lee |
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| Rok vydání: | 2012 |
| Předmět: |
Cisplatin
Cancer Research Chemotherapy Pathology medicine.medical_specialty business.industry medicine.medical_treatment Stomach Case Report Perigastric medicine.disease Metastasis Dissection medicine.anatomical_structure Oncology Neuroendocrine carcinoma Medicine Abdomen Unknown primary neoplasms business Lymph nodes Etoposide medicine.drug |
| Zdroj: | Cancer Research and Treatment : Official Journal of Korean Cancer Association |
| ISSN: | 2005-9256 1598-2998 |
| DOI: | 10.4143/crt.2012.44.4.271 |
| Popis: | Neuroendocrine carcinomas from an unknown primary site are uncommon. The authors report on a case of neuroendocrine carcinoma in a perigastric lymph node (LN) with no primary site. A 52-year-old male patient with early gastric adenocarcinoma underwent treatment by endoscopic submucosal dissection, and, six months later, findings on a computed tomographic scan of the abdomen revealed a LN enlargement measuring 2.0 cm in the perigastric region. The patient underwent subtotal gastrectomy and regional LN dissection under a suggestive preoperative diagnosis of gastric adenocarcinoma with LN metastasis. However, microscopically, no residual tumor was found in the stomach, and the perigastric LN showed poorly differentiated neuroendocrine carcinoma (PDNEC). After an extensive workup, no primary site was identified. The patient also received four cycles of etoposide and cisplatin. Despite its extremely rare incidence, this case suggests that PDNEC of an unknown primary site is limited to a single site, and that resection should be considered in combination with chemotherapy. |
| Databáze: | OpenAIRE |
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