In vitro synergistic activity between bismuth subcitrate and various antimicrobial agents against Campylobacter pyloridis (C. pylori)
| Autor: | J Breyssens, D L Van Caekenberghe |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1987 |
| Předmět: |
inorganic chemicals
medicine.drug_class Antibiotics Microbial Sensitivity Tests Pharmacology digestive system Microbiology Agar dilution Oxolinic acid medicine Organometallic Compounds Pharmacology (medical) Norfloxacin Antibacterial agent Chemistry Campylobacter Drug Synergism Antimicrobial equipment and supplies bacterial infections and mycoses digestive system diseases Anti-Bacterial Agents Infectious Diseases Bismuth Subcitrate Drug Therapy Combination Ofloxacin medicine.drug Research Article |
| Popis: | The in vitro interactions between bismuth subcitrate and a variety of antimicrobial agents against 12 Campylobacter pyloridis (C. pylori) isolates were studied by the agar dilution checkerboard technique. The combination of bismuth subcitrate with the older quinolone, oxolinic acid, produced synergistic activity against all strains. This observation, however, could not be extended to the (aryl) fluoroquinolones, norfloxacin, ofloxacin, and difloxacin, since synergy was rare or absent when bismuth subcitrate was combined with these antibiotics. Among the other antimicrobial agents tested, rifampin and the beta-lactams frequently showed showed MICs for C. pyloridis similar to those of bismuth subcitrate. |
| Databáze: | OpenAIRE |
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