Risk stratification in acute coronary syndrome: Evaluation of the GRACE and CRUSADE scores in the setting of a tertiary care centre
Autor: | Calvin Kienbacher, Harald Herkner, Raphael van Tulder, Wolfgang Schreiber, Verena Fuhrmann, Katharina Tscherny, Dominik Roth |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
Male
medicine.medical_specialty Acute coronary syndrome Population Risk management tools Hemorrhage 030204 cardiovascular system & hematology Cardiovascular Medicine Risk Assessment Severity of Illness Index Decision Support Techniques Tertiary Care Centers 03 medical and health sciences 0302 clinical medicine Percutaneous Coronary Intervention Internal medicine Severity of illness medicine Humans 030212 general & internal medicine Myocardial infarction Hospital Mortality Acute Coronary Syndrome education Aged education.field_of_study Original Paper Management of acute coronary syndrome business.industry General Medicine Middle Aged medicine.disease Area Under Curve Conventional PCI Female Risk assessment business |
Zdroj: | International Journal of Clinical Practice |
ISSN: | 1742-1241 1368-5031 |
Popis: | Objective Risk assessment plays a decisive role in the management of acute coronary syndrome (ACS). The GRACE and the CRUSADE scores are among the most frequently used risk assessment tools. We aimed to compare the performance of the GRACE and CRUSADE risk scores to predict in‐hospital mortality and major bleeding in a contemporary ACS population at a high‐volume academic hospital. Methods All patients treated for ACS from January 1, 2006 to December 31, 2015 at a tertiary care centre were prospectively enrolled. We calculated GRACE and CRUSADE risk scores. We compared the discrimination capacity of both scores for in‐hospital mortality and major bleeding. Results In total 4087 patients (1151 [28.2%] female; age 62 ± 14 years) were included. Among these 2218 (54.3%) were diagnosed with ST‐elevation myocardial infarction, 113 (2.8%) died in hospital and major bleeding occurred in 65 (1.6%). Discrimination capacity for in‐hospital mortality of the GRACE score was superior to the CRUSADE score (receiver operator characteristic area under the curve (AUC) 0.91 (95% CI 0.89‐0.93) vs 0.83 (95% CI 0.80‐0.86); P |
Databáze: | OpenAIRE |
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