Tick-borne encephalitis (TBE) virus prevalence and virus genome characterization in field-collected ticks (Ixodes ricinus) from risk, non-risk and former risk areas of TBE, and in ticks removed from humans in Germany
Autor: | Bernd Hoffmann, Martin Beer, Christine Klaus, Jochen Süss, U. Hering, Konrad Sachse, B. Mielke |
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Rok vydání: | 2010 |
Předmět: |
Adult
Male Microbiology (medical) TBEV strain 263 Ixodes ricinus Adolescent virus genome characterization Molecular Sequence Data Encephalitis Viruses Tick-Borne ticks Young Adult tick-borne encephalitis (TBE) Germany parasitic diseases Prevalence medicine Animals Humans Neudoerfl strain Child Aged Aged 80 and over Ixodes biology Reverse Transcriptase Polymerase Chain Reaction Zoonosis Tick-borne encephalitis Sequence Analysis DNA General Medicine Middle Aged bacterial infections and mycoses medicine.disease biology.organism_classification Virology TBE virus (TBEV) Flavivirus Tick-borne encephalitis virus Human Experimentation Infectious Diseases Child Preschool RNA Viral Female Encephalitis Ixodidae |
Zdroj: | Clinical Microbiology and Infection. 16:238-244 |
ISSN: | 1198-743X |
DOI: | 10.1111/j.1469-0691.2009.02764.x |
Popis: | Tick-borne encephalitis (TBE) is recognized as the most important viral tick-borne zoonosis in 27 countries in Europe. In this study, ticks were collected in Germany from two non-risk areas in the states of Saxony-Anhalt and Mecklenburg-Western Pomerania, where several single human TBE cases have occurred in recent years. Ticks were also collected from a region in Thuringia, known to be a former risk area for TBE virus (TBEV), where numerous human cases were reported between 1960 and 1975. Detection of TBEV RNA was conducted by real-time RT-PCR. No TBEV was detected in any field-collected ticks. However, ticks were also collected from volunteers living in Bavaria. Three of 239 ticks from this collection were positive for TBEV genome and two genetically distinct TBEV strains were detected and characterized. |
Databáze: | OpenAIRE |
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