Higher maternal BMI early in pregnancy is associated with overweight and obesity in young adult offspring in Thailand

Autor: Amaraporn Rerkasem, Kittipan Rerkasem, Sakaewan Ounjaijean, Sakda Pruenglampoo, Ampica Mangklabruks, Kanokwan Kulprachakarn, Antika Wongthanee, José G. B. Derraik
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Adult
Male
medicine.medical_specialty
Offspring
030209 endocrinology & metabolism
Overweight
Carotid Intima-Media Thickness
03 medical and health sciences
Young Adult
0302 clinical medicine
Pregnancy
Risk Factors
medicine
Humans
030212 general & internal medicine
Obesity
Prospective Studies
Young adult
Body mass index
Mother
Anthropometry
Obstetrics
business.industry
DOHaD
Public Health
Environmental and Occupational Health
Developmental origins of health and disease
Public Health
Global Health
Social Medicine and Epidemiology
medicine.disease
Thailand
Weight
Pregnancy Complications
Folkhälsovetenskap
global hälsa
socialmedicin och epidemiologi
Metabolism
Programming
Adult Children
Female
medicine.symptom
Underweight
Public aspects of medicine
RA1-1270
business
Follow-Up Studies
Research Article
Zdroj: BMC Public Health, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Public Health
Popis: Background Rates of overweight and obesity among women of reproductive age have been steadily increasing worldwide and in Thailand. There is mounting evidence that maternal obesity during pregnancy is associated with an increased risk of obesity and other adverse health outcomes in the offspring, but such data are lacking for Thailand. We examined the associations between maternal body mass index (BMI) and anthropometry (particularly the likelihood of obesity) and cardiometabolic parameters in young adult offspring. Methods This was a prospective follow-up study of a birth cohort in Chiang Mai (Thailand). Pregnant women carrying singletons were recruited at their first antenatal visit ( Results We assessed 628 young adults (54% were females) at 20.6 ± 0.5 years of age (range 19.1–22.1 years). The young adult offspring of mothers with overweight/obesity was 14.1 kg (95%CI 9.7, 18.5; p 2 (95%CI 2.26, 4.67; p 2 (95%CI 3.67, 8.68; p 2 increase in maternal BMI, the adjusted odds ratio (aOR) of offspring obesity was 25% greater (95%CI 1.10, 1.42; p p p = 0.010) compared to young adults born to mothers with normal weight or underweight, respectively. There were no observed associations between maternal BMI status and offspring metabolism or blood pressure. Discussion Maternal overweight/obesity early in pregnancy was associated with increased BMI and greater odds of obesity in their young adult offspring in Thailand. These findings highlight the public health importance of fostering healthier lifestyle choices among women of reproductive age.
Databáze: OpenAIRE
Externí odkaz: