Review of the effects of dietary fat on experimental mammary gland tumorigenesis: Role of lipid peroxidation
| Autor: | Clifford W. Welsch |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
medicine.medical_specialty
Free Radicals Linoleic acid Mammary gland Breast Neoplasms Rodentia Biology medicine.disease_cause Biochemistry Linoleic Acid Lipid peroxidation Mice chemistry.chemical_compound Mammary Glands Animal Immune system Physiology (medical) Internal medicine medicine Carcinoma Animals Humans Dietary fat Peroxidase Mammary Neoplasms Experimental medicine.disease Dietary Fats Lipids medicine.anatomical_structure Endocrinology Linoleic Acids chemistry Female Carcinogenesis Function (biology) |
| Zdroj: | Free Radical Biology and Medicine. 18:757-773 |
| ISSN: | 0891-5849 |
| Popis: | The purpose of this communication is threefold, that is, (1) to review and critique the studies designed to examine the interrelationship between dietary fat and experimental rodent mammary gland tumorigenesis, (2) to assess the influence of dietary fat on growth of human breast carcinoma transplants in immunodeficient mice, and (3) to examine and discuss the role of products of lipid peroxidation in these tumorigenic processes. It is concluded from this review and critique that the amount and type of dietary fat can significantly influence the development and/or growth of rodent mammary gland tumors and growth of human breast carcinomas in immune deficient mice. Dietary fat can be either stimulatory or inhibitory to these tumorigenic processes, phenomena that could be a function, at least in part, of the generation of products of lipid peroxidation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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