Brain Tumor-Enhancement Visualization and Morphometric Assessment: A Comparison of MPRAGE, SPACE, and VIBE MRI Techniques
Autor: | Michael Reinert, Emanuele Pravatà, E. Prodi, Gianna C Riccitelli, Daniela Distefano, Elisa Ventura, Alessandro Cianfoni, A. Kaelin-Lang, L. Danieli |
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Rok vydání: | 2018 |
Předmět: |
Adult
Male Neuronavigation Wilcoxon signed-rank test Brain tumor Contrast Media Neuroimaging 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Imaging Three-Dimensional Flip angle Image Interpretation Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging Aged Mri techniques business.industry Brain Neoplasms Adult Brain Glioma Middle Aged medicine.disease Mr imaging Magnetic Resonance Imaging Visualization Female Neurology (clinical) Brain examination Nuclear medicine business 030217 neurology & neurosurgery |
Zdroj: | AJNR Am J Neuroradiol |
ISSN: | 1936-959X |
Popis: | BACKGROUND AND PURPOSE: Postgadolinium MR imaging is crucial for brain tumor diagnosis and morphometric assessment. We compared brain tumor enhancement visualization and the “target” object morphometry obtained with the most commonly used 3D MR imaging technique, MPRAGE, with 2 other routinely available techniques: sampling perfection with application-optimized contrasts by using different flip angle evolutions (SPACE) and volumetric interpolated brain examination (VIBE). MATERIALS AND METHODS: Fifty-four contrast-enhancing tumors (38 gliomas and 16 metastases) were assessed using MPRAGE, VIBE, and SPACE techniques randomly acquired after gadolinium-based contrast agent administration on a 3T scanner. Enhancement conspicuity was assessed quantitatively by calculating the contrast rate and contrast-to-noise ratio, and qualitatively, by consensus visual comparative ratings. The total enhancing tumor volume and between-sequence discrepancy in the margin delineation were assessed on the corresponding 3D target objects contoured with a computer-assisted software for neuronavigation. The Wilcoxon signed rank and Pearson χ(2) nonparametric tests were used to investigate between-sequence discrepancies in the contrast rate, contrast-to-noise ratio, visual conspicuity ratings, tumor volume, and margin delineation estimates. Differences were also tested for 1D (Response Evaluation Criteria in Solid Tumors) and 2D (Response Assessment in Neuro-Oncology) measurements. RESULTS: Compared with MPRAGE, both SPACE and VIBE obtained higher contrast rate, contrast-to-noise ratio, and visual conspicuity ratings in both gliomas and metastases (P range |
Databáze: | OpenAIRE |
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