Equal survival rates for first, second, and third episodes of Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome
| Autor: | Frame Dl, Vigdorth Em, Robert P. Baughman, Michael N. Dohn |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Pediatrics
medicine.medical_specialty Acquired immunodeficiency syndrome (AIDS) Recurrence Immunopathology Odds Ratio Internal Medicine medicine Humans In patient Prospective Studies AIDS-Related Opportunistic Infections business.industry Pneumonia Pneumocystis Respiratory disease Prognosis medicine.disease respiratory tract diseases Survival Rate Pneumonia Treatment Outcome Pneumocystis carinii Immunology Viral disease Complication business |
| Zdroj: | Archives of Internal Medicine. 152:2465-2470 |
| ISSN: | 0003-9926 |
| DOI: | 10.1001/archinte.152.12.2465 |
| Popis: | BACKGROUND Second and subsequent episodes of acute Pneumocystis carinii pneumonia (PCP) are reported to have a worse prognosis than initial episodes in patients with the acquired immunodeficiency syndrome. We tested the hypothesis that survival rates of first, second, and subsequent episodes of acute PCP in patients with the acquired immunodeficiency syndrome are equal. METHODS Analysis of the outcomes in prospective series of patients with the acquired immunodeficiency syndrome treated for acute PCP over 5 years. RESULTS Survival rates of 222 PCP occurrences by episode number were: first, 86%; second, 84%; third, 88%; and fourth, 67%. Survival rates for the first, second, and third episodes were not significantly different. Second and third episodes had a larger proportion of patients with mild disease than initial episodes. CONCLUSIONS Survival rates for first, second, and third episodes of PCP in patients with the acquired immunodeficiency syndrome are not different. In contrast to earlier articles, treatment for second and third episodes of acute PCP may be as successful as in initial episodes. |
| Databáze: | OpenAIRE |
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