| Autor: |
Brunnert, Marcus, Fischer, Paul, Urfer, Wolfgang |
| Jazyk: |
angličtina |
| Rok vydání: |
2002 |
| Předmět: |
|
| DOI: |
10.17877/de290r-15209 |
| Popis: |
The expanding availability of protein data enforces the application of empirical methods necessary to recognize protein structures. In this paper a sequence-structure alignment method is described and applied to various Ubiquitin-like folded Ras-binding domains. On the basis of two probability functions that evaluate similarities between the occurrence of amino-acids in the primary and secondary protein structure, different versions of simple scoring functions are proposed. The application of the program ’PLACER’ that uses a dynamic programming approach enables the search for an optimal sequence-structure alignment and the prediction of the secondary structure. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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