Pathophysiology of sepsis-associated brain dysfunction: an experimental study of cerebral microdialysis and mitochondrial function
| Autor: | I Mello, C Vargas-Lopes, P Kurtz, C Madeira, Fernando A. Bozza, Luciano Cesar Pontes Azevedo, R Panizzutti |
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| Rok vydání: | 2013 |
| Předmět: |
Pathology
medicine.medical_specialty Septic shock business.industry Brain dysfunction Critical Care and Intensive Care Medicine Bioinformatics medicine.disease medicine.disease_cause Pathophysiology Sepsis Cerebral microdialysis Poster Presentation medicine business Neuroinflammation Function (biology) Oxidative stress |
| Zdroj: | Critical Care |
| ISSN: | 1364-8535 |
| DOI: | 10.1186/cc11961 |
| Popis: | Pathophysiology of brain dysfunction associated with sepsis is still poorly understood. Potential mechanisms involve oxidative stress, neuroinflammation and blood-brain barrier alterations. Our purpose was to study the metabolic alterations and markers of mitochondrial dysfunction in a clinically relevant model of septic shock. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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