Infant brain imaging using magnetoencephalography: Challenges, solutions, and best practices

Autor: Maggie D. Clarke, Alexis N. Bosseler, Julia C. Mizrahi, Erica R. Peterson, Eric Larson, Andrew N. Meltzoff, Patricia K. Kuhl, Samu Taulu
Rok vydání: 2022
Předmět:
Zdroj: Human Brain Mapping. 43:3609-3619
ISSN: 1097-0193
1065-9471
DOI: 10.1002/hbm.25871
Popis: The excellent temporal resolution and advanced spatial resolution of magnetoencephalography (MEG) makes it an excellent tool to study the neural dynamics underlying cognitive processes in the developing brain. Nonetheless, a number of challenges exist when using MEG to image infant populations. There is a persistent belief that collecting MEG data with infants presents a number of limitations and challenges that are difficult to overcome. Due to this notion, many researchers either avoid conducting infant MEG research or believe that, in order to collect high-quality data, they must impose limiting restrictions on the infant or the experimental paradigm. In this article, we discuss the various challenges unique to imaging awake infants and young children with MEG, and share general best-practice guidelines and recommendations for data collection, acquisition, preprocessing, and analysis. The current article is focused on methodology that allows investigators to test the sensory, perceptual, and cognitive capacities of awake and moving infants. We believe that such methodology opens the pathway for using MEG to provide mechanistic explanations for the complex behavior observed in awake, sentient, and dynamically interacting infants, thus addressing core topics in developmental cognitive neuroscience.
Databáze: OpenAIRE
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