Response of lipoprotein(a) levels to therapeutic life-style change in obese African–Americans
| Autor: | Otelio S. Randall, Shichen Xu, Kachi Illoh, Muluemebet Ketete, Habteab B. Feseha, John Kwagyan, Michelle Wrenn, Carl Tilghman |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Diet Reducing Body Mass Index chemistry.chemical_compound High-density lipoprotein Internal medicine Humans Medicine Obesity Child Exercise Life Style Triglycerides Aged biology medicine.diagnostic_test Triglyceride business.industry Cholesterol Cholesterol HDL Estrogen Replacement Therapy Lipoprotein(a) Middle Aged Lipids Black or African American Lipoproteins LDL Endocrinology chemistry Low-density lipoprotein HMG-CoA reductase biology.protein Female lipids (amino acids peptides and proteins) Hydroxymethylglutaryl-CoA Reductase Inhibitors Cardiology and Cardiovascular Medicine business Lipid profile Lipoprotein |
| Zdroj: | Atherosclerosis. 172:155-160 |
| ISSN: | 0021-9150 |
| DOI: | 10.1016/j.atherosclerosis.2003.09.017 |
| Popis: | Lipoprotein(a) (Lp(a)) is regarded as an independent risk factor for Atherosclerotic cardiovascular disease. The objectives of this study were: to determine the effects of diet and exercise on Lp(a) and to evaluate the relation of Lp(a) with the lipid profile (total serum cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) cholesterol). Baseline Lp(a), body mass index (BMI) and the lipid profiles were measured in 343 Obese (BMI >30kg/m(2)) African-Americans. After a 3-month intervention of diet and exercise by 105 participants, their lipids were re-measured. Baseline Lp(a) levels ranged from 1.2 to 280mg/dl. Lp(a) was inversely associated with triglyceride (P |
| Databáze: | OpenAIRE |
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