Sarcopenia as a prognostic predictor of liver cirrhosis: a multicentre study in China
| Autor: | Zhi-Wen Shi, Pei-Mei Shi, Li-Yuan Zhang, Chun-Qing Zhang, Hong Yu, Yuan-Yuan Luo, Xin Zeng, Si-Min Jin, Li-Fen Wang, Jia-Jun Yu, Wei Tan, Wei-Fen Xie |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Liver Cirrhosis China Sarcopenia medicine.medical_specialty Diagnostic criteria Cirrhosis Cirrhosis‐related complications Survival Prognosis prediction Diseases of the musculoskeletal system Age and sex Severity of Illness Index Liver function End Stage Liver Disease Physiology (medical) Internal medicine Female patient Humans Medicine Orthopedics and Sports Medicine Nutritional screening Muscle Skeletal business.industry QM1-695 Malnutrition Original Articles Nutritional assessment Prognosis medicine.disease Comorbidity RC925-935 Human anatomy L3 skeletal muscle index Cohort Female Original Article business |
| Zdroj: | Journal of Cachexia, Sarcopenia and Muscle Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 1948-1958 (2021) |
| ISSN: | 2190-6009 2190-5991 |
| Popis: | Background Diagnostic criteria for sarcopenia have not been established in Chinese. This study established criteria based on the L3‐skeletal muscle index (L3‐SMI) and assessed its value for outcomes predicting in cirrhotic Chinese patients. Methods Totally 911 subjects who underwent a CT scan at two centres were enrolled in Cohort 1 (394 male and 417 female subjects, aged 20–80 years). The data of those subjects younger than 60 years (365 male and 296 female subjects) were used to determine the reference intervals of the L3‐SMI and its influencing factors. Cohort 2 consisted of 480 patients (286 male and 184 female patients) from three centres, and their data were used to investigate the prevalence of sarcopenia and evaluate the value of L3‐SMI for predicting the prognosis and complications of cirrhosis. Results Age and sex had the greatest effects on the L3‐SMI (P 14 (RR = 4.310, 95% CI 2.091–8.882, P |
| Databáze: | OpenAIRE |
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