Reliability enhancement and estimation in multisite clinical trials
| Autor: | Bonnie McRee, Thomas F. Babor, F K Del Boca |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Estimation
Research design Data collection Variables Process (engineering) business.industry media_common.quotation_subject Reproducibility of Results General Medicine Personality Assessment Clinical trial Alcoholism Outcome and Process Assessment Health Care Clinical Protocols Risk analysis (engineering) Humans Multicenter Studies as Topic Medicine business Quality assurance Reliability (statistics) Randomized Controlled Trials as Topic media_common |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1946-6005 0363-468X |
| DOI: | 10.15288/jsas.1994.s12.130 |
| Popis: | Clinical trials, particularly those in addictions research, often rely on self-report data for primary dependent variables, and it is imperative to evaluate and to minimize both random and systematic error. This article describes methods for enhancing and assessing reliability of measurement in multisite clinical research. It begins with an overview of the two major approaches to evaluating the reliability of psychiatric diagnosis and verbal self-reports. A model of the interview process is then described, and the major sources of inconsistency that arise in the data collection process are identified. Based on the model, staff selection criteria, training techniques and quality assurance procedures are recommended for enhancing the reliability of interview assessments, and a research design appropriate for evaluating reliability in multisite clinical investigations is proposed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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