Increasing Incidence of Pediatric Inflammatory Bowel Disease in Spain (1996–2009)

Autor: Inaki Irastorza, Manuel Barreiro de Acosta, ANA ECHARRI, Carolina Gutiérrez-Junquera, Luis Peña-Quintana, Begoña Pérez-Moneo Agapito, Ricardo Torres-Peral, Daniel Carpio, Esther Ramos Boluda, DAVID GIL ORTEGA, Santiago Jiménez
Rok vydání: 2013
Předmět:
Zdroj: Inflammatory Bowel Diseases. 19:73-80
ISSN: 1078-0998
Popis: Background: Although pediatric inflammatory bowel disease (IBD) diagnosis has increased in the last decades in Spain, there are no consistent epidemiologic data. Our aim was to describe the changing pattern of pediatric IBD incidence in Spain in the last 14 years. Methods: A retrospective survey of patients diagnosed below 18 years of age in the period 1996–2009 was performed. Patients' data were obtained from the hospitals' databases. To avoid reduced accrual of cases diagnosed by adult physicians, adult IBD units in referral centers were invited to participate. Seventy-eight centers participated in our survey. Rates of incidence were calculated using age-stratified population-based epidemiologic data. Incidence rates were compared for the last 14 years (1996–2009). Results: In total, data from 2107 patients were obtained: 1,165 Crohn's disease (CD, 55.3%), 788 ulcerative colitis (UC, 37.4%), and 154 IBD unclassified. The sex distribution was 56.4% male, with higher predominance for CD (59.3%) as compared to UC (52.8%) and IBD unclassified (53.2%) (P = 0.012). The median age at diagnosis was 12.3 years (p25–75 9.7–14.6) with significant differences between diseases. IBD incidence increased from 0.97 to 2.8/100,000 inhabitants
Databáze: OpenAIRE