Selective Inhibition of Formation of Deoxyribonucleic Acid in Escherichia coli by Mitomycin C
| Autor: | Junichi Kawamata, T. Taguchi, Shigeru Shiba, A. Terawaki |
|---|---|
| Rok vydání: | 1959 |
| Předmět: |
Streptomyces caespitosus
Multidisciplinary biology Biochemical Phenomena medicine.drug_class Mitomycin Antibiotics Mitomycin C Antineoplastic Agents DNA Selective inhibition medicine.disease_cause biology.organism_classification Anti-Bacterial Agents chemistry.chemical_compound chemistry Biochemistry Escherichia coli medicine Antibacterial activity Antibiotics Antitubercular |
| Zdroj: | Nature. 183:1056-1057 |
| ISSN: | 1476-4687 0028-0836 |
| DOI: | 10.1038/1831056a0 |
| Popis: | PREVIOUS studies with mitomycin C, a new antibiotic isolated from Streptomyces caespitosus by Wakaki et al., have demonstrated antibacterial activity as well as a marked antitumour effect1,2. In the course of investigating the mechanism of the actions of mitomycin C, evidence was obtained that this antibiotic selectively inhibits the synthesis of deoxyribonucleic acid in Escherichia coli B. |
| Databáze: | OpenAIRE |
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