Caparratriene, an Active Sesquiterpene Hydrocarbon from Ocotea caparrapi

Autor:	Carlos Maldonado, Mohamad B. Ksebati, Eduardo Palomino, Maya B. Kempff
Rok vydání:	1996
Předmět:	Magnetic Resonance Spectroscopy Spectrophotometry Infrared Stereochemistry Pharmaceutical Science Growth inhibitory Colombia Pharmacognosy Sesquiterpene Gas Chromatography-Mass Spectrometry Analytical Chemistry Terpene chemistry.chemical_compound Drug Discovery Tumor Cells Cultured Humans Pharmacology chemistry.chemical_classification Leukemia Experimental Plants Medicinal biology Organic Chemistry Caparratriene Lauraceae biology.organism_classification Antineoplastic Agents Phytogenic Hydrocarbon Complementary and alternative medicine chemistry Molecular Medicine Spectrophotometry Ultraviolet Ocotea Sesquiterpenes
Zdroj:	Journal of Natural Products. 59:77-79
ISSN:	1520-6025 0163-3864
Popis:	Caparratriene (1), a new sesquiterpene hydrocarbon with significant growth inhibitory activity (IC50 = 3.0 +/- 0.5 x 10(-6) M) against CEM leukemia cells, was isolated from the oil of Ocotea caparrapi (Nates) Dugand. The structure of 1, determined by spectroscopic techniques, corresponded to (E,E)-3,7,11-trimethyl-2,4,10-dodecatriene (C15H26).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff71c95fd763c9ef23d3c7c66449f8d https://doi.org/10.1021/np960012r Zobrazit plný text záznamu