MicroRNAs are potential prognostic and therapeutic targets in diabetic osteoarthritis
| Autor: | Chen Feiyan, Shi Jingsheng, Chen Jie, Wang Si-qun, Huang Gang-yong, Wu Jianguo, Xia Jun, Wei Yibing |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism Life quality Osteoarthritis Bioinformatics Diabetes Complications Type ii diabetes Endocrinology Degenerative disease Quality of life Diabetes mellitus microRNA medicine Animals Homeostasis Humans Orthopedics and Sports Medicine business.industry Disease progression General Medicine Prognosis medicine.disease MicroRNAs Cartilage Diabetes Mellitus Type 2 Gene Expression Regulation Disease Progression Quality of Life Physical therapy business |
| Zdroj: | Journal of Bone and Mineral Metabolism. 33:1-8 |
| ISSN: | 1435-5604 0914-8779 |
| DOI: | 10.1007/s00774-014-0628-0 |
| Popis: | Osteoarthritis is an aging-related degenerative disease that severely influences the elders’ life quality. However, there have been few clinical approaches available until now. Currently, more knowledge of the pathology of osteoarthritis has been illustrated. Especially, diabetes can be the only predictor of osteoarthritis. Due to its outstanding characteristics, MicroRNA has been considered as an efficient target in treating diseases. In this review, we will discuss a new insight focusing on the roles of microRNA in the progression of osteoarthritis-induced by diabetes, especially type II diabetes mellitus. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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