GONADOTROPHIN SECRETION IN THE SECOND HALF OF THE MENSTRUAL CYCLE: A COMPARISON OF WOMEN WITH NORMAL CYCLES, LUTEAL PHASE DEFECTS AND DISTURBED FOLLICULAR DEVELOPMENT
| Autor: | Karl-Martin Pirke, Ulrich Schweiger, Reinhard J. Tuschl, A. Broocks |
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| Rok vydání: | 1990 |
| Předmět: |
endocrine system
medicine.medical_specialty medicine.drug_class Endocrinology Diabetes and Metabolism media_common.quotation_subject Pulsatile flow Luteal Phase Luteal phase Biology Endocrinology Internal medicine Follicular phase medicine Humans Secretion Ovarian Diseases Ovarian follicle Progesterone reproductive and urinary physiology Menstrual cycle media_common Estradiol Luteinizing Hormone Menstruation medicine.anatomical_structure Estrogen Female Follicle Stimulating Hormone Gonadotropin Secretory Rate hormones hormone substitutes and hormone antagonists |
| Zdroj: | Clinical Endocrinology. 32:25-32 |
| ISSN: | 1365-2265 0300-0664 |
| DOI: | 10.1111/j.1365-2265.1990.tb03746.x |
| Popis: | In order to study the relationship between episodic gonadotrophin secretion and alterations of ovarian hormone secretion, we examined women with normal menstrual cycles (n = 26), luteal phase defects (n = 10) or disturbed follicular oestradiol secretion (n = 8) as established by daily (except weekends) determinations of oestradiol and progesterone. Pulsatile gonadotrophin secretion was studied during the luteal phase or the second half of the menstrual cycle sampling at 15 min intervals for 12 h. LH and FSH mean concentrations and LH pulse frequency were significantly (P less than 0.01) increased in the group with disturbed follicular development in the presence of decreased oestradiol (E2) and progesterone (P4) levels. In women with luteal phase defects mean LH and FSH concentrations and pulsatile LH secretion showed a nonsignificant trend to lower values in the presence of significantly decreased P4 concentrations during the luteal phase. |
| Databáze: | OpenAIRE |
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